site stats

Ctr copper transporter family protein

Webin copper transport is currently lacking. According to computer algorithm analyses, Ctr family members contain three mem-brane-spanning domains, within which most of protein se-quence similarity lies. Biochemical and microscopy experi-ments in yeast and human cells have suggested that Ctr family members are integral membrane proteins that ... WebFeb 8, 2002 · This is the first report on the biochemical characterization of the human copper transporter hCtr1, which is important for understanding mechanisms for mammalian copper transport at the plasma membrane. The trace metal copper is an essential cofactor for a number of biological processes including mitochondrial oxidative …

Human copper transporter 2 is localized in late endosomes and …

WebOct 1, 2024 · The moss Physcomitrium (Physcomitrella) patens is a bryophyte that provides genetic information about the adaptation to the life on land by early Embryophytes and is a reference organism for comparative evolutionary studies in plants. Copper is an essential micronutrient for every living organism, its transport across the plasma membrane is … WebMar 1, 2004 · A different class of transporter known as the SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all … diamond studs for guys https://itstaffinc.com

Structural and Functional Diversity Among the Members of CTR…

WebFigure 1. Bioinformatic analysis identifies C. thermophilum copper transporters. A, model showing a homotrimeric Ctr1/Ctr3 family protein complex with key Cys and Met residues involved in Cu + transport connected with a dashed red circle and key Gly residues involved in trimer stability via transmembrane helical packing highlighted with a red box. … WebSolute carrier family. The solute carrier ( SLC) group of membrane transport proteins include over 400 members organized into 66 families. [1] [2] Most members of the SLC group are located in the cell membrane. The SLC gene nomenclature system was originally proposed by the HUGO Gene Nomenclature Committee ( HGNC) and is the basis for the ... WebNov 1, 2006 · CTR1 belongs to the CTR (or SLC31A) family that includes CTR1/2 and P-type copper transporting ATPases (ATP7A and B). It is a 23-kDa channel-like transporter which has a unique pore for the transport of copper and three trans-membranes domains that oligomerize to form a functional trimer [85]. ciscycling

Molecular and functional analyses of COPT/Ctr-type copper transporter ...

Category:Copper transport protein (Ctr1) levels in mice are tissue …

Tags:Ctr copper transporter family protein

Ctr copper transporter family protein

Copper homeostasis in grapevine: Functional characterization …

WebApr 1, 2013 · Copper is a vital mineral for many organisms, yet it is highly toxic as demonstrated by serious health concerns associated with its deficiency or excess accumulation. The SLC31 (CTR) family of...

Ctr copper transporter family protein

Did you know?

Webthe SLC31 or Ctr family of proteins mediates cellular copper uptake. These high-affinity copper transporters exist in all eukaryotes and their discovery has provided new insights … WebApr 21, 2011 · The rice COPT-type gene family consists of seven members (COPT1 to COPT7). However, only two, COPT1 and COPT5, have been characterized for their functions in Cu transport. Results: All members of the rice COPT family have the conserved features of known COPT/Ctr-type Cu transporter genes.

WebJul 21, 2014 · The family of proteins responsible for the transport of Cu in the reduced form is the COPT transport protein (copper transporter protein). These proteins are formed by five... WebThe reported Cu transporters are mainly from the COPT/Ctr protein family. Cu might be co-transported by COPT2, COPT3, and COPT4 with COPT6. ... Yuan M, Li X, Xiao J, Wang S (2011) Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice. BMC Plant Biol 11(1):69

WebSep 25, 2024 · CTR1 belongs to a family of Copper Transporters that has at least six members (CTR1-6) among various organisms. Structural and functional divergence of the CTRs from lower organisms to mammals shed light on how the regulation of this protein family is modulated depending on the requirement and availability of copper. WebJan 5, 2024 · Enables copper ion transmembrane transporter activity. Involved in cellular copper ion homeostasis; copper ion transport; and regulation of heart rate. Located in plasma membrane. Is expressed in adult head. Orthologous to several human genes including SLC31A1 (solute carrier family 31 member 1). [provided by Alliance of …

WebOur research interests are primarily directed towards developing novel MS-based proteomics methods and applying them to the biomedical studies. LC-MS-based method …

WebCopper uptake is regulated by CTR (copper transporter) family of proteins, which are highly conserved. High affinity copper uptake is facilitated by Ctr1 and Ctr3 in Saccharomyces cerevisiae and ... diamond studs on guysWebSep 12, 2007 · High-affinity cellular copper uptake is mediated by the CTR (copper transporter) 1 family of proteins. The highly homologous hCTR (human CTR) 2 protein has been identified, but its function in copper uptake is currently unknown. To characterize the role of hCTR2 in copper homoeostasis, epitope-tagged hCTR2 was transiently … diamond studs onlineWebCenter for Biotechnology & Drug Design (CDBB) Institution: Georgia State University URL: http://www.biology.gsu.edu/BDD/index.html Description: vaccines, drug design ... diamond studs lab grownWebNational Center for Biotechnology Information cis cyclohexan 1 2 diolWebApr 2, 2014 · Some pieces of evidence reported that Cu can be also taken up by other bivalent cations transporters, as the Natural Resistance Associated Macrophage Proteins (NRAMP), Zrt-and Irt-like proteins... diamond studs only in okWebStudies were conducted to determine distribution of the copper transporter, Ctr1, a transmembrane protein responsible for cellular copper uptake, in adult mice and in … diamond studs only promotional codeWebAAA Cooper Transportation offers an excellent opportunity for employees across a breadth of skills, experience, and backgrounds. Click the careers button to find out more about … cis-cyclohexanediol density