site stats

Fstl1 monocyte

WebJun 1, 2024 · Furthermore, FSTL1 is an acidic cysteine-rich secreted protein and a member of the SPARC family based on protein domain similarity [5]. Indeed, FSTL1 binds to disco-interacting protein2 homolog A (DIP2A), which is a receptor for FSTL1 as evidenced by molecular interaction analyses by Ouchi et al. [6]. WebOur FSTL1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed in Rabbit, Goat, Mouse and Rat. These antibodies have been verified by Relative expression to confirm specificity to FSTL1. Find the FSTL1 antibody that fits your needs.

Anti-FSTL1 Antibodies Invitrogen - Thermo Fisher Scientific

WebFeb 8, 2024 · Myeloid- specific FSTL1- knock out (FSTL1 M- OK) mice were constructed to explore the function and mechanism of macrophage FSTL1 in 3 murine models of liver fibrosis induced by carbon tetrachloride injection, bile duct ligation or a methionine-deficient and choline-deficient diet. Results FSTL1 expression was significantly elevated WebFSTL1 and TREM1 were significantly increased in cells with miR-181b downregulation. (c) miR-181b bound to the 3′-UTR regions of FSTL1 and TREM1, and binding was interrupted in mutant FSTL1 and ... cornwall\u0027s population https://itstaffinc.com

FSTL1 aggravates OVA-induced inflammatory responses by

WebSep 1, 2024 · Our understanding of the mechanisms responsible for the progression of chronic kidney disease (CKD) is incomplete. Microarray analysis of kidneys at 4 and 7 weeks of age in Col4a3-/- mice, a model of progressive nephropathy characterized by proteinuria, interstitial fibrosis, and inflammation, revealed that Follistatin-like-1 (Fstl1) … WebApr 11, 2011 · Follistatin-like 1 (Fstl1), first identified as a TGF-β1–inducible gene (), encodes a secreted extracellular glycoprotein belonging to the Fst-SPARC family, whose … cornwall\u0027s heritage coast

Follistatin-like 1 (FSTL1) is a prognostic biomarker and

Category:Targeting FSTL1 Prevents Tumor Bone Metastasis and Consequent …

Tags:Fstl1 monocyte

Fstl1 monocyte

FSTL1 promotes liver fibrosis by reprogramming macrophage …

WebOct 17, 2011 · The monocyte cell line U937, which does not express FSTL1, was transfected with a plasmid encoding FSTL1 and stimulated with phorbol myristate acetate and lipopolysaccharide. Cell supernatants were assayed for IL-6, IL-8, monocyte chemotactic protein 1 (MCP-1), and FSTL1 by enzyme-linked immunosorbent assay. WebFeb 9, 2024 · FSTL1 expression was significantly elevated in macrophages from fibrotic livers of both humans and mice. Myeloid-specific FSTL1 deficiency effectively attenuated the progression of liver fibrosis. ... as demonstrated by attenuated infiltration of monocytes/macrophages and neutrophils and decreased expression of proinflammatory …

Fstl1 monocyte

Did you know?

WebNational Center for Biotechnology Information WebAug 31, 2024 · Follistatin-like protein 1 (Fstl1), a glycoprotein widely expressed in human and mouse tissues, is a tumor suppressor in various cancers and a regulator in macrophage polarization. However, how Fstl1 affects the crosstalk between breast cancer cells and macrophages remains unclear.

WebFollistatin like-1 (FSTL1) is a secreted glycoprotein involved in a series of physiological and pathological processes. However, its contribution to the development of cancer, especially the pathogenesis of NSCLC, remains to be elucidated. We explored the expression, function, and molecular mechanis … WebOct 14, 2013 · We found that FSTL1 plays a dual role in bone metastasis—in one way by mediating tumor cell invasion and bone tropism but also in a second way by expanding a population of pluripotent mesenchymal stem-like CD45 …

WebFSTL1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. WebMar 29, 2024 · Follistatin-like 1 (FSTL1) is a secreted glycoprotein displaying expression changes during development and disease, among which cardiovascular disease, cancer, …

Webfstl1. sections. tissue brain single cell type tissue cell type pathology disease immune cell blood protein subcellular cell line structure metabolic about. introduction history …

WebMar 24, 2024 · The FSTL1 protein was significantly less in lung tissues of Fstl1 +/− mice, and the increased FSTL1 protein after silica treatment was reduced in Fstl1 +/− mice (Fig. 2a). cornwall\u0027s pubWebFeb 8, 2024 · demonstrated by attenuated infiltration of monocytes/ macrophages and neutrophils and decreased expression of proinflammatory factors. FSTL1M- OK … cornwall\\u0027s kenmore squareWebDec 1, 2024 · FSTL1 silencing largely counteracts miR-579-3p knockdown-induced effects in M.tb-infected THP-1 macrophages. ... and further studies are needed to confirm these … cornwall\\u0027s populationWebJun 2, 2024 · FSTL1 is a cardioprotective factor [ 4 ], pro-fibrotic agent [ 5 ], and a bi-directional regulator of tumor based upon the origin of the tumorigenic cell line [ 6 ]. Asthmatic patients express high levels of FSTL1 in plasma and bronchoalveolar lavage fluid (BALF) compared with health subjects [ 7 ]. fantasy thrusterWebResults FSTL1 expression was significantly elevated in macrophages from fibrotic livers of both humans and mice. Myeloid-specific FSTL1 deficiency effectively attenuated the … fantasy throwing needlesWebMar 21, 2024 · FSTL1 is a potential mediator of inflammation and insulin resistance in obesity. These results suggest that FSTL-1 may act on the NLRP3 inflammasome to … fantasy thumbnailsWebMay 17, 2014 · Follistatin-like protein 1 (FSTL1), a secreted glycoprotein, also named TSC-36 [transforming growth factor (TGF)β 1-stimulated clone 36] or FRP (follistatin-related protein), was originally cloned from the mouse osteoblastic cell line MC3T3-E1 [].FSTL1 is widely expressed in human and mouse tissues, although its expression was found to be … cornwall\u0027s pub menu